The effect of a hydrogel made by Nigella sativa L. on acne vulgaris: A randomized double-blind clinical trial. View abstract. 1993;31:55-60. View abstract. Bayrak, O., Bavbek, N., Karatas, O. F., Bayrak, R., Catal, F., Cimentepe, E., Akbas, A., Yildirim, E., Unal, D., and Akcay, A. Nigella sativa protects against ischaemia/reperfusion injury in rat kidneys. Dtsch.Tierarztl.Wochenschr. Islam, S. K., Ahsan, M., Hassan, C. M., and Malek, M. A. Antifungal activities of the oils of Nigella sativa seeds. Scientia Pharmaceutica (Austria) 2006;74:159-173. Arzneimittelforschung. Alam MA, Nasiruddin M, Haque SF, Khan RA. Int J Exp.Pathol. 2. Shoieb, A. M., Elgayyar, M., Dudrick, P. S., Bell, J. L., and Tithof, P. K. In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone. Hosseinzadeh, H., Parvardeh, S., Nassiri-Asl, M., and Mansouri, M. T. Intracerebroventricular administration of thymoquinone, the major constituent of Nigella sativa seeds, suppresses epileptic seizures in rats. Boskabady, M. H., Javan, H., Sajady, M., and Rakhshandeh, H. The possible prophylactic effect of Nigella sativa seed extract in asthmatic patients. View abstract. Eur.J Pharmacol. The effect of Nigella sativa Linn. Effects of borneol and thymoquinone on TNBS-induced colitis in mice. Therefore, you may wonder whether eating black sesame seeds is also good for hair and skin health. Skin damage caused by radiation therapy (radiation dermatitis). Mol.Cell Biochem 2003;245(1-2):127-139. View abstract. Effect of herbal melanin on IL-8: a possible role of Toll-like receptor 4 (TLR4). Effect of different levels of feed added black seed (Nigella sativa L.) on the performance of broiler chicks. Alizadeh-Naini M, Yousefnejad H, Hejazi N. The beneficial health effects of Nigella sativa on Helicobacter pylori eradication, dyspepsia symptoms, and quality of life in infected patients: A pilot study. Effect of black cumin (Nigella sativa) on heart rate, some hematological values, and pancreatic beta-cell damage in cadmium-treated rats. View abstract. 2010;92(2):395-412. 11-1-1999;67(2):135-142. View abstract. View abstract. View abstract. Black seed oil, also called black cumin oil, comes from the black cumin (Nigella sativa) plant and has been used for thousands of years in traditional medicine. 2006;12(2):100-104. Int Immunopharmacol. Dahri, A. H., Chandiol, A. M., Rahoo, A. Pak.J Pharm Sci. View abstract. J Physiol Pharmacol. Arzneimittelforschung. Shafei, M. N., Boskabady, M. H., and Parsaee, H. Effect of aqueous extract from Nigella sativa L. on guinea pig isolated heart. Black seed powder mixed in honey: actually tastes great Black seed also helps as an analgesic, is good for weight loss, is anti-inflammatory and has many other great properties including stimulating the liver, helping elasticity of blood vessels, and stimulating tumor cell death while inhibiting kidney cell death. J Enzyme Inhib.Med Chem. 2008;28(1):11-14. Kruk, I., Michalska, T., Lichszteld, K., Kladna, A., and Aboul-Enein, H. Y. J Agric.Food Chem. Hawsawi, Z. Nephrol.Dial.Transplant. The effects of black seed supplementation on cardiovascular risk factors in patients with nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled clinical trial. Insufficient Evidence to Rate Effectiveness for... Next to red peppers, you can get the most vitamin C from ________________. View abstract. Historically, black seed has been used for headache, toothache, nasal congestion, and intestinal worms. Endocrine. Nigella sativa improves glycemic control and ameliorates oxidative stress in patients with type 2 diabetes mellitus: placebo controlled participant blinded clinical trial. 2005;41:388-393. Arayne, M. S., Sultana, N., Mirza, A. Tohoku J Exp.Med 2003;201(4):213-219. View abstract. 1970;20(10):1574-1577. Med Princ Pract. Tangyuenyongwatana, P., Kowapradit, J., Opanasopit, P., and Gritsanapan, W. Cellular transport of anti-inflammatory pro-drugs originated from a herbal formulation of Zingiber cassumunar and Nigella sativa. View abstract. Zaoui, A., Cherrah, Y., Mahassini, N., Alaoui, K., Amarouch, H., and Hassar, M. Acute and chronic toxicity of Nigella sativa fixed oil. Black Cumin Seed Carrier Oil is cold pressed from the seeds of the Fennel Flower. View abstract. Protective effects of thymoquinone and desferrioxamine against hepatotoxicity of carbon tetrachloride in mice. 8. View abstract. View abstract. Oshchepkova, IuI, Veshkurova, O. N., Rogozhin, E. A., Musoliamov, A. K., Smirnov, A. N., Odintsova, T. I., Egorov, TsA, Grishin, E. V., and Salikhov, ShI. Farah, N., Benghuzzi, H., Tucci, M., and Cason, Z. Clinical evaluation of Nigella sativa seeds for the treatment of hyperlipidemia: a randomized, placebo controlled clinical trial. Acta Microbiol.Pol. Res Vet.Sci 2010;88(3):400-404. Type 2 diabetes – Researchers found that just two grams daily of black seed could result in reduced fasting blood sugar levels, along with decreased insulin resistance, and increased beta-cell function in the pancreas. Haqqaq EG, Abou-Moustafa MA, Boucher W, Theoharides TC. View abstract. 2009;35(3):344-349. J Ethnopharmacol 2015;175:147-52. 2019 Mar;80(3):176-177. View abstract. Potential hepatoprotective effects of vitamin E and Nigella sativa oil on hepatotoxicity induced by chronic exposure to malathion in human and male albino rats. View abstract. View abstract. Al Majed, A. Res Vet.Sci 2005;79(3):219-223. Indian J Exp.Biol. View abstract. Evaluation of safety and efficacy profile of Nigella sativa oil as an add-on therapy, in addition to alpha-keto analogue of essential amino acids in patients with chronic kidney disease. The effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) - 1, Nesfatin-1 and anthropometric features in patients with Hashimoto's thyroiditis: a randomized controlled trial. Sangi, S., Ahmed, S. P., Channa, M. A., Ashfaq, M., and Mastoi, S. M. A new and novel treatment of opioid dependence: Nigella sativa 500 mg. J Ayub.Med Coll.Abbottabad. View abstract. Bullous drug eruption to Nigella sativa oil: Consideration of the use of a herbal medicine - clinical report and review of the literature. J Ethnopharmacol. Antimicrobial activity of essential oil, fixed oil and unsaponifiable matter of Nigella sativa Linn. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use black seed. View abstract. Biochem Mol Biol Int 1999;47:153-9. 2008;44:477-482. J Altern.Complement Med 2008;14(9):1137-1144. 2015;15(1):64-71. B. 2000;72(1-2):299-304. Planta Med 2005;71(8):739-742. 10-18-2003;2(1):6. 2008;103(2):109-118. Ali, B. H. and Blunden, G. Pharmacological and toxicological properties of Nigella sativa. View abstract. Haq, A., Lobo, P. I., Al Tufail, M., Rama, N. R., and Al Sedairy, S. T. Immunomodulatory effect of Nigella sativa proteins fractionated by ion exchange chromatography. Long-term kidney disease (chronic kidney disease or CKD). View abstract. 10-30-2009;2(4-5):163-172. International Journal of Pharmacognosy (Netherlands). Kocyigit, Y., Atamer, Y., and Uysal, E. The effect of dietary supplementation of Nigella sativa L. on serum lipid profile in rats. El Wakil, S. S. Evaluation of the in vitro effect of Nigella sativa aqueous extract on Blastocystis hominis isolates. A. Thymoquinone induces apoptosis through activation of caspase-8 and mitochondrial events in p53-null myeloblastic leukemia HL-60 cells. View abstract. Black seed oil and perioperative serotonin syndrome: A case report. Biomed.Sci Instrum. Vance, S. H., Benghuzzi, H., Wilson-Simpson, F., and Tucci, M. Thymoquinone supplementation and its effect on kidney tubule epithelial cells in vitro. Post-coital contraceptive efficacy of the seeds of Black seed in rats. The possible prophylactic effect of Nigella sativa seed aqueous extract on respiratory symptoms and pulmonary function tests on chemical war victims: a randomized, double-blind, placebo-controlled trial. J Egypt Soc.Parasitol. Salomi NJ, Nair SC, Jayawardhanan KK, et al. J Mol.Histol. Phytomedicine. 2008;46(12):805-810. El Gazzar, M. A. Thymoquinone suppressses in vitro production of IL-5 and IL-13 by mast cells in response to lipopolysaccharide stimulation. J Ethnopharmacol. Hamdy, N. M. and Taha, R. A. Boskabady, M. H., Keyhanmanesh, R., and Saadatloo, M. A. Relaxant effects of different fractions from Nigella sativa L. on guinea pig tracheal chains and its possible mechanism(s). 2020;69(1):49-52. The effect of a herbal water-extract on histamine release from mast cells and on allergic asthma. 2007;37(3):801-813. Biomed.Sci Instrum. Ayaz, E., Yilmaz, H., Ozbek, H., Tas, Z., and Orunc, O. Meddah, B., Ducroc, R., El Abbes, Faouzi M., Eto, B., Mahraoui, L., Benhaddou-Andaloussi, A., Martineau, L. C., Cherrah, Y., and Haddad, P. S. Nigella sativa inhibits intestinal glucose absorption and improves glucose tolerance in rats. 6-1-2010;79(11):1640-1647. View abstract. Al Ghamdi, M. S. The anti-inflammatory, analgesic and antipyretic activity of Nigella sativa. 2002;46(2):195-201. View abstract. View abstract. Phytother.Res 2009;23(9):1295-1298. Khattab, M. M. and Nagi, M. N. Thymoquinone supplementation attenuates hypertension and renal damage in nitric oxide deficient hypertensive rats. Effect of Nigella sativa on blood hemostatic function in rats. Dehavay F, Kolivras A, Scheers C. Local and systemic adverse skin reactions following the use of herbal products believed to contain Nigella sativa seeds and oil. Boskabady, M. H., Shafei, M. N., and Parsaee, H. Effects of aqueous and macerated extracts from Nigella sativa on guinea pig isolated heart activity. Gheita TA, Kenawy SA. The effects of Nigella sativa on atherosclerosis and its new risk factors in hypercholesterolemic rabbits. View abstract. Folia Microbiol. Biomed.Sci Instrum. View abstract. View abstract. Neuropharmacology 2005;49(4):456-464. Black seed oil and black seed extract are POSSIBLY SAFE when medical amounts are used short-term. Effect of Nigella sativa (N. sativa L.) and oxidative stress on the survival pattern of MCF-7 breast cancer cells. It is believed to boost the immune system and have antibacterial, anti-inflammatory, anti-fungal, and antiparasitic properties. 2005;11(4):BR106-BR110. Med Sci Monit. Effect of Nigella sativa (Black Seed) and thymoquinone on blood glucose in albino rats. Nigella sativa L. - active compounds, biological properties. Medications that cause sleepiness are called sedatives. View abstract. Kaleem, M., Kirmani, D., Asif, M., Ahmed, Q., and Bano, B. Biochemical effects of Nigella sativa L seeds in diabetic rats. Arch Pharm.Res 2009;32(1):75-78. Assayed, M. E. Radioprotective effects of black seed (Nigella sativa) oil against hemopoietic damage and immunosuppression in gamma-irradiated rats. Yes, the purpose of this article was to show that black seeds are good for cancer. View abstract. Aggarwal, B. View abstract. Where did you or where do you plan to purchase this product? Ibrahim, Z. S., Ishizuka, M., Soliman, M., ElBohi, K., Sobhy, W., Muzandu, K., Elkattawy, A. M., Sakamoto, K. Q., and Fujita, S. Protection by Nigella sativa against carbon tetrachloride-induced downregulation of hepatic cytochrome P450 isozymes in rats. Int Immunopharmacol. 2008;20(3):72-74. 2003;88(1):63-68. Phytomedicine 2004;11(1):56-64. Eur J Cancer Prev 1999;8:435-40. Kooshki A, Tofighiyan T, Rastgoo N, Rakhshani MH, Miri M. Effect of Nigella sativa oil supplement on risk factors for cardiovascular diseases in patients with type 2 diabetes mellitus. 2001;110(5-6):333-345. A., Al Sawaf, H. A., Al Sohaibani, M. O., and Al Bekairi, A. M. Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity. Phytother Res 2012;26:1246-8. A., and Memon, R. A. Stop using black seed at least two weeks before a scheduled surgery. Toxicol.Mech.Methods 2008;18(9):725-731. 10-30-2009;2(4-5):163-172. Pharmaceutical Biology (Netherlands) 1999;(37):391-395. Richards, L. R., Jones, P., Hughes, J., Benghuzzi, H., and Tucci, M. LNCaP cells exposed to ceramic drug delivery treatment with epigallocatechin-3-gallate, thymoquinone, and tannic acid. Current research suggests black … Fouda, A. M., Daba, M. H., Dahab, G. M., and Sharaf El-Din, O. The role of black seed in the proliferation and biochemical marker levels of Hep-2 cells. essential oils and their major constituents, thymoquinone and beta-elemene. Pak.J Pharm.Sci 2007;20(4):268-273. Biomed.Sci Instrum. Kanter, M., Coskun, O., and Budancamanak, M. Hepatoprotective effects of Nigella sativa L and Urtica dioica L on lipid peroxidation, antioxidant enzyme systems and liver enzymes in carbon tetrachloride-treated rats. View abstract. Historically, black seed has been used for headache, toothache, nasal congestion, asthma, arthritis, and intestinal worms. PLoS One 2015;10:e0113486. J Ethnopharmacol. 2004;93(1):19-23. Fundam.Clin Pharmacol. Studies on the antimicrobial activity of Black seed seed (black cumin). Also, you can use black seeds for healing diarrhea, constipation, gas, hemorrhoids, flu, bronchitis, cough, allergies, asthma, high blood pressure, menstruation, high cholesterol, etc. Fundam Clin Pharmacol 2008;22:447-52. View abstract. 2003;17(10):1209-1214. Photochem.Photobiol. Zaoui, A., Cherrah, Y., Lacaille-Dubois, M. A., Settaf, A., Amarouch, H., and Hassar, M. [Diuretic and hypotensive effects of Nigella sativa in the spontaneously hypertensive rat]. A. Thymoquinone protects renal tubular cells against tubular injury. 2000;50(9):832-836. View abstract. J Ethnopharmacol. Braz.J Med Biol.Res 2007;40(6):839-847. Fararh, K. M., Ibrahim, A. K., and Elsonosy, Y. Farhangi MA, Dehghan P, Tajmiri S, Abbasi MM. Electron Physician. View abstract. 2003;17(4):299-305. Busari AA, Adejare AA, Shodipe AF, Oduniyi OA, Ismail-Badmus KB, Oreagba IA. Some cardiovascular effects of the dethymoquinonated Nigella sativa volatile oil and its major components alpha-pinene and p-cymene in rats. View abstract. Res Vet.Sci 2004;77(2):123-129. View abstract. View abstract. Ann.Saudi Med 2001;21(3-4):242-244. Awad, E. M. and Binder, B. R. In vitro induction of endothelial cell fibrinolytic alterations by Nigella sativa. A., Mostafa, A. Effect of Nigella sativa supplementation on oxidative stress and antioxidant parameters: A meta-analysis of randomized controlled trials. Biomed.Sci Instrum. Int J Clin Pharmacol.Ther 2008;46(6):295-306. Int J Diabetes Dev.Ctries. Namazi N, Larijani B, Ayati MH, Abdollahi M. The effects of Nigella sativa L. on obesity: a systematic review and meta-analysis. A., Abdel-Naim, A. Int J Biochem Cell Biol. 3. Mouhajir F and et al. Planta Med 2010;76(3):218-222. What factors influenced or will influence your purchase? 2000;22(9):729-740. Nigella sativa concoction induced sustained seroreversion in HIV patient. 2006;6(7):1135-1142. 2008;23(7):2206-2212. cyclosporine pharmacokinetics. View abstract. Parvardeh S and et al. In Wistar rats 115 ( 2 ):408-415 administration on prevention of febrile neutropenia during chemotherapy among children with lymphoblastic. Seed has been shown to be changed and henna leaves provide a soothing effect in the tomb of King.. 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